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Genomics

By studying the genetic instructions of living organisms, ESR is helping to improve our health and the health of the world around us, for a better Aotearoa.

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About

Our research in genomics, a fast moving and evolving field of science, covers many areas, like studying humans, the environment, and solving mysteries in forensic research using DNA clues.

Every living thing, from microbes to people, has its own DNA, containing a set of instructions called a genome. This genome tells an organism how to function, grow and stay healthy. By studying genomes, ESR is learning more about taking care of ourselves and our environment. 

We're also helping scientists in Aotearoa work together to get better at understanding genomes, so everyone can benefit from knowledge of genetic code.

ESR has genomics and bioinformatics expertise and capability which includes:

  • Forensic biology, including DNA and mRNA expertise 

  • Analysis and advice on the behaviour of pathogenic bacteria and viruses in biowaste, soil and water 

  • Identification of virus and bacteria relevant to public health

  • Water microbiology testing and research 

  • Food forensic investigations to identify source in foodborne disease 

Microbial Genomics

Microbial Genomics

Microbial genomics is a technology that gives us information about the genomic sequence of harmful pathogens. Microbial genomics can provide us with information about the DNA make up of different bacteria and viruses, including harmful ones that cause human illness. 


The use of microbial genomics spans multiple areas of field of research across ESR. 

Microbial genomics at ESR

Human health
  • Public health surveillance of notifiable diseases that cause human illness. Learn more.

  • Viral detection in wastewater. Learn more.

  • ESR uses the latest technology to provide its next generation sequencing capacity and performs the national sequencing for all COVID-19 positive samples. We use a combination of platforms to obtain the most reliable genome data, these technologies are supplied by Illumina and Oxford Nanopore. 

  • Clinical genomics led by Dr Rhys White. Collaboration with Dr Max Bloomfield, Awanui Labs, based at the Wellington Regional Hospital.

  • ESR also manages the Genomics special interest group, and the New Zealand Microbiology Network.

Human Genomics 

Human Genomics 

The human genome is made up of 22 autosomes and a pair of sex chromosomes. A genome sequence establishes the order of DNA nucleotides or bases (A, C, G, and T) that make up an organism's DNA. This information is critical to understanding how our bodies develop and function. Our human genomics work includes: 

  • Collaborating with clinicians and surgeons at Wellington Hospital with the aim of bringing the benefits of lower cost, quicker turn-around sequencing to aid in clinical decision making.

  • DNA methylation, transcriptomics and small non-coding RNA and their role and utility as biomarkers in metabolic diseases - in particular obesity and type-two diabetes. This incorporates a Social Systems aspect to understand what makes a successful community-led intervention and is part of Healthier Lives He Oranga Hauora National Science Challenge.

  • Epigenetics for equitable cardiovascular risk prediction.

  • Affordable, disruptive sequencing for community empowerment.

Genomics Aotearoa Consortia

Genomics Aotearoa consortia

ESR is a partner in Genomics Aotearoa, a science platform supporting advanced genomics research in New Zealand. It is an alliance between New Zealand Universities and Crown research institutes, which provides a collaborative platform to grow New Zealand’s capability, build international connections and develop tools and technologies to support genomics research. 

Specialist services

Specialist services

Our genomic experts use the latest technology to provide next generation sequencing across many of our focus areas, including forensic biology, foodborne pathogens and faecal source tracking.

Testing & analysis

Testing & analysis services

Testing & analysis services

ESR combines state-of-the-art genome sequencing with advanced scientific expertise to identify environmental, food safety and quality issues and help solve complex problems.

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Experts in the area