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KPC carbapenemase gene PCR

Antibiotic Reference Laboratory

Demonstration of the presence of a KPC carbapenemase gene by PCR.

KPC carbapenemases are most commonly identified in Klebsiella pneumoniae, but have also been identified in other Enterobacterales. The KPC β-lactamase confers resistance to all β-lactams, including cephalosporins, monobactams and carbapenems. Several types of KPC carbapenemase have been described.

This test is appropriate for isolates that screen positive for carbapenemase in the CLSI modified carbapenem inactivation method.

 

Area

Health Science

Lab name

Antibiotic Reference Laboratory

Lab location

Kenepuru Science Centre, Porirua

Test name

KPC carbapenemase gene PCR

Organisms

Enterobacterales

Requested for surveillance

yes

Notice required

no

Routine turnaround time

6 working days for reference specimens

Sample requirements

Pure culture

Media requirements

A slope of any medium that supports the growth of the organism

Pre-transport requirements

Ambient temperature

Transport requirements

Ambient temperature

Unacceptable sample types

Clinical specimens will not be accepted.

How results reported

The results will state whether the KPC gene was detected

Referral link

Form