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Investigation into stutter ratio variance

Abstract

Weusten and HerbergsCitation1 proposed a simple and intuitive model for predicting the expected height of stutter peaks and the variance about this expectation. Empirical verification of this model is valuable both for the theoretical understanding of the PCR process and for the practical implementation of many interpretation models for DNA mixtures. This paper confirms Weusten and Herbergs’ prediction that the variance of stutter height is inversely proportional to template, with a study of 99 Identifiler profiles.

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