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OXA-48-like carbapenemase gene PCR

Registry Details

Area Health Science
Lab name Antibiotic Reference Laboratory
Lab location Kenepuru Science Centre, Porirua
Test name OXA-48-like carbapenemase gene PCR
Organisms Enterobacteriaceae
Requested for surveillance yes
Notice required no
Routine turnaround time 6 working days for reference specimens
Culture requirements Pure culture
Media requirements A slope of any medium that supports the growth of the organism
Pre-transport requirements Ambient temperature
Transport requirements Ambient temperature
Unacceptable sample types Clinical specimens will not be accepted.
How results reported The result will state whether the OXA-48-like gene was detected
Referral link Form

Details

Demonstration of the presence of an OXA-48-like carbapenemase gene by PCR.

OXA-48-like carbapenemases are most commonly identified in Klebsiella pneumoniae and other Enterobacteriaceae. OXA-48-like β-lactamases confer resistance to carbapenems, but not the extended-spectrum cephalosporins nor monobactams.

This test is appropriate for isolates that screen positive for carbapenemase in the CLSI modified carbapenem inactivation method.