ESR undertakes a variety of research activities into the epidemiology of infectious disease and specialist aspects of disease-causing organisms.
Recent and ongoing research activities include:
- determination of the diversity in vaccine target sites on meningococci causing epidemic disease;
- comparison of New Zealand and overseas isolates of Salmonella Typhimurium DT160 using suppression subtractive hybridisation;
- analysis of Campylobacter and Burkholderia populations using multilocus sequence typing;
- use of reverse genetics for the production of vaccine seed strains;
- occurrence, circulation and evolution of oral poliovirus vaccine strains in New Zealand;
- prevalence, persistence and localisation of norovirus in shellfish;
- survival and persistence of norovirus, adenovirus and hepatitis A on fresh produce;
- detection of noroviruses and animal calciviruses in faecal specimens and environmental waters;
- risk-targeted study of influenza zoonosis;
- examination of microdiversities in the 'epidemic meningococcal disease strain' that are associated with geographic source, time, place, disease clustering or immunisation status;
- determination of diversity in pertussis toxin and pertactin genes in Bordetella pertussis;
- genetic diversity in group A streptococci causing invasive disease relative to M (emm) types.